근거 검색식

진료지침 검색 자료원

검색자료원	검색 건수	채택 건수
PubMed (www.pubmed.gov)	100	5
Cochrane Library (www.thecochranelibrary.com)	3	0
Embase (www.embase.com)	6	1
National Guideline Clearing House (http://www.guideline.gov/)	14	2(1:중복)
CMA Infobase (https://www.cma.ca/En/Pages/clinical-practice-guidelines.aspx)	15	0
SIGN (http://www.sign.ac.uk/our-guidelines.html)	0	0
NICE (http://www.nice.org.uk)	3	1

문헌고찰을 위한 검색식으로 PubMed에서(prostate cancer OR prostate carcinoma OR prostate malignant) AND ((Guideline[ptyp] OR Practice Guideline[ptyp]) ((“2007/01/01”[PDAT] : “2016/12/31”[PDAT]) AND “humans”[MeSH Terms] AND English[lang])를 사용하여 100건의 문헌을 검색하였고 Cochrane Library에서는(prostate cancer OR prostate carcinoma OR prostate malignant) AND Guideline의 검색식을 사용하여 3건의 자료를 검색하였으며 EmBase에서(prostate cancer OR prostate carcinoma OR prostate malignant) AND (‘prostate cancer’/exp OR Prostatic carcinoma OR Prostatic malignant) AND ‘practice guideline’/exp AND [humans]/lim AND [20072016]/py AND ‘practice guideline’/de AND ‘article’/it을 사용하여 6건의 문헌을 검색하였다. 국가별 검색 자료원 중 미국의 National Guideline Clearing House에서(prostate cancer OR prostate carcinoma OR prostate malignant)의 검색식을 사용하여 14건의 자료를 검색하였고 캐나다의 CMA Infobase에서는(prostate and cancer)의 검색식을 사용하여 15건의 자료를 검색하였다. 영국의 SIGN 과 NICE에서는 주제별 검색을 통해 각각 0건과 3건의 자료를 검색하였다. 국내 자료는 대한비뇨기종양학회를 통해 제공받았다.

검색결과

검색 DB	기존	재검색1(P,I)	재검색2
MEDLINE	4187 (P+I 수술) 3491 (P+I 요법) 989 (P+I 모니터링)	1358 (P+I 수술) 788 (P+I 요법) 298 (P+I 모니터링)	428 (P+I 수술) 322 (P+I 요법) 66 (P+I 모니터링)
EMBASE	-	3083 (P+I 수술) 2121 (P+I 요법) 756 (P+I 모니터링)	1095(P+I 수술) 939 (P+I 요법) 184 (P+I 모니터링)
Cochrane			87 (P+I 수술) 109 (P+I 요법) 13 (P+I 모니터링)

연구설계 필터: SR or RCT or Observational studies, 연도제한(2015 이후), 언어제한: 영어, 동물연구 배제

(1) Ovid MEDLINE(R) In-Process & Other Non-Indexed Citations and Ovid MEDLINE(R) 1946 to Present

검색일:2017.6.2
구분	연번	검색어	검색 결과
P P종합	1	Prostatic Neoplasms/	110409
	2	prostate tumor.tw.	2940
	3	((prostate or prostatic) adj3 (cancer* or carcinoma* or malignan* or tumor* or tumour* or neoplas* or adenocarcinoma* or adenoma*)).tw	121989
	4	or/1-3	142755
	5	limit 4 to yr=”2015 -Current”	21008
	6	limit 5 to english language	20065
I 수술 종합1	7	Prostatectomy/	25150
	8	Prostatectomy.tw.	25267
	9	nerve-sparing surgery.tw.	202
	10	bone protective agent$.tw.	21
	11	Lymph Node Excision/ or pelvic lymph node dissection.tw.	29932
	12	or/7-11	75220
I-요법 종합2	13	radiation therapy.tw. or Radiotherapy/	101081
	14	Gonadotropin-Releasing Hormone/ or GnRH agonist.tw.	27885
	15	(antiandrogen therapy or anti-androgen therapy).tw.	389
	16	(hormone therapy or adjuvant adj3 therapy).tw	39239
	17	(docetaxel chemotherapy or docetaxel monotherapy).tw.	517
	18	(androgen blockage or androgen blocade).tw	47
	19	or/13-18	164409
I-모니터링 종합3	20	active surveillance.tw.	5286
	21	Watchful Waiting/	2473
	22	psa monitoring.tw.	40
	23	or/20-22	7253
	24	6 and 12 (P+I수술)	2890
	25	6 and 19 (P+I요법)	1630
	26	6 and 23 (P+I모니터링)	724
P and I	27	OR/24-26	4530
Filter (SR or RCT)	28	“Review Literature as Topic”/ or systematic review.mp. OR exp Meta-Analysis/ OR Meta-Analys*.mp. OR exp Randomized Controlled Trials/ OR Random*. mp. OR RCT.mp. OR exp Controlled Clinical Trial/ OR exp Placebo Effect/ OR exp Placebos/ OR Placebo.mp. OR trial.mp.	1769686
Filter (Observational Studies)	29	exp Epidemiologic Studies/ OR exp Case-Control Studies/ OR exp Cohort Studies/ OR exp Cross-Sectional Studies/ OR exp Seroepidemiologic Studies/ OR Case control.mp. OR cohort stud*.mp. OR cohort analys*.mp. OR Follow up stud*.mp. OR observational stud*.mp. OR Longitudinal.mp. OR Retrospective.mp. OR Cross sectional.mp.	2473615
	30	27 and (28 or 29)	2107
동물 연구 제외	31	Animals/ not (Animals/ and Humans/)	4378590
배제	32	note/ or editorial/ or letter/ or Comment/ or news/ or case report/ or case reports/ or conference abstract/	3435446
	33	30 not (31 or 32)	2061
최종	34	33 and (mortality or survival).tw.	655
	35	24 and 34 (P+I수술)	428
	36	25 and 34 (P+I요법)	322
	37	26 and 34 (P+I모니터링)	66

(2) Ovid- Embase 1980 to 2017 Week 22

검색일:2017.6.2
구분	연번	검색어	검색 결과
P P종합	1	prostate tumor/	25539
	2	prostate tumor.tw.	4000
	3	((prostate or prostatic) adj3 (cancer* or carcinoma* or malignan* or tumor* or tumour* or neoplas* or adenocarcinoma* or adenoma*)).tw	166495
	4	or/1-3	173467
	5	limit 4 to yr=”2015 -Current”	31103
	6	limit 5 to english language	30262
I 수술 종합1	7	Prostatectomy/	46353
	8	Prostatectomy.tw.	37810
	9	nerve-sparing surgery.tw.	355
	10	bone protective agent$.tw.	31
	11	Lymph Node Excision/ or pelvic lymph node dissection.tw.	39868
	12	or/7-11	88873
I-요법 종합2	13	radiation therapy.tw. or Radiotherapy/	158699
	14	Gonadotropin-Releasing Hormone/ or GnRH agonist.tw.	34383
	15	(antiandrogen therapy or anti-androgen therapy).tw.	479
	16	(hormone therapy or adjuvant adj3 therapy).tw	54585
	17	(docetaxel chemotherapy or docetaxel monotherapy).tw.	839
	18	(androgen blockage or androgen blocade).tw	63
	19	or/13-18	240528
I-모니터링 종합3	20	active surveillance.tw.	8378
	21	Watchful Waiting/	2927
	22	psa monitoring.tw.	74
	23	or/20-22	7177
	24	6 and 12 (P+I수술)	5772
	25	6 and 19 (P+I요법)	3492
	26	6 and 23 (P+I모니터링)	1302
P and I	27	OR/24-26	8747
Filter (SR or RCT)	28	“Review Literature as Topic”/ or systematic review.mp. OR exp Meta-Analysis/ OR Meta-Analys*.mp. OR exp Randomized Controlled Trials/ OR Random*. mp. OR RCT.mp. OR exp Controlled Clinical Trial/ OR exp Placebo Effect/ OR exp Placebos/ OR Placebo.mp. OR trial.mp.	1993683
Filter (Observational Studies)	29	exp Epidemiologic Studies/ OR exp Case-Control Studies/ OR exp Cohort Studies/ OR exp Cross-Sectional Studies/ OR exp Seroepidemiologic Studies/ OR Case control.mp. OR cohort stud*.mp. OR cohort analys*.mp. OR Follow up stud*.mp. OR observational stud*.mp. OR Longitudinal.mp. OR Retrospective.mp. OR Cross sectional.mp.	4459197
	30	27 and (28 or 29)	5149
동물 연구 제외	31	Animals/ not (Animals/ and Humans/)	1275043
배제	32	note/ or editorial/ or letter/ or Comment/ or news/ or case report/ or case reports/ or conference abstract/	4010900
	33	30 not (31 or 32)	4786
최종	34	33 and (mortality or survival).tw.	1720
	35	24 and 34 (P+I수술)	1095
	36	25 and 34 (P+I요법)	939
	37	26 and 34 (P+I모니터링)	184

(3) Cochrane Library

검색일:2017.6.2
구분	연번	검색어	검색 결과
P P종합	1	MeSH descriptor: [Prostatic Neoplasms] explode all trees	4139
	2	prostate tumor.tw.	2206
	3	((prostate or prostatic) NEAR (cancer* or carcinoma* or malignan* or tumor* or tumour* or neoplas* or adenocarcinoma* or adenoma*))	9875
	4	#1 or #2 or #3	20065
I 수술 종합1	5	MeSH descriptor: [Prostatectomy] explode all trees	1783
	6	Prostatectomy or “nerve-sparing surgery” or “bone protective agent*”	2642
	7	MeSH descriptor: [Lymph Node Excision] explode all trees	202
	8	“pelvic lymph node dissection“	119
	9	#5 or #6 or #7 or #8	4591
I-요법 종합2	10	MeSH descriptor: [Radiotherapy] explode all trees	6179
	11	MeSH descriptor: [Gonadotropin-Releasing Hormone] explode all trees	101081
	12	(“radiation therapy” or “GnRH agonist”) ;ti.ab.kw	6676
	13	“antiandrogen therapy” or “anti-androgen therapy” or “hormone therapy”	2558
	14	adjuvant near therapy	9980
	15	“docetaxel chemotherapy” or “docetaxel monotherapy”	142
	16	“androgen blockage” or “androgen blocade”	8
	17	#10 or #11 or #12 or #13 or #14 or #15 or #16	19526
I-모니터링 종합3	18	“active surveillance“	384
	19	MeSH descriptor: [Watchful Waiting] explode all trees	2473
	20	PSA monitoring	160
	21	#18 or #19 or #20	759
	22	#4 and #9 (P+I수술)	833
	23	#4 and #17 (P+I요법)	1236
	24	#4 and #21 (P+I모니터링)	116
P and I	25	#22 or #23 or #24 Publication Year from 2015 to 2017	179
	26	#22 and #25 (P+I수술) Cochrane Reviews (5) Other Reviews (0) Trials (82) Methods Studies (0) Technology Assessments (2) Economic Evaluations (0) Cochrane Groups (0)	87
	27	#23 and #25 (P+I요법) Cochrane Reviews (12) Other Reviews (0) Trials (97) Methods Studies (0) Technology Assessments (3) Economic Evaluations (0) Cochrane Groups (0)	109
	28	#24 and #25 (P+I모니터링) Cochrane Reviews (1) Other Reviews (0) Trials (12) Methods Studies (0) Technology Assessments (1) Economic Evaluations (0) Cochrane Groups (0)	13

그림 1. 체계적 문헌검색 분류표(수술)

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