클라미디아감염증 편집하기 (부분)

===생식기클라미디아감염===

*메타분석에 따르면 doxycycline 100mg 1일 2회 경구 7일 요법과 azithromycin 1g 경구 단회 요법은 동일한 효과를 보였고, 부작용의 발현에도 차이가 없었다.<ref name="Doxycycline and azithromycin for prevention of chlamydial persistence or recurrence one month after treatment in women.">Hillis SD, Coles FB, Litchfield B, et al. Doxycycline and azithromycin for prevention of chlamydial persistence or recurrence one month after treatment in women. A use-effectiveness study in public health settings. Sex Transm Dis 1998;25:5-11. </ref><ref name="Single dose of azithromycin for the treatment of genital chlamydial infections in adolescents.">Hammerschlag MR, Golden NH, Oh MK, et al. Single dose of azithromycin for the treatment of genital chlamydial infections in adolescents. J Pediatr 1993;122:961-965. </ref><ref name="The role of azalide antibiotics in the treatment of Chlamydia.">Johnson RB. The role of azalide antibiotics in the treatment of Chlamydia. Am J Obstet Gynecol 1991;164(6 Pt 2):1794-1796. </ref><ref name="Cost-effectiveness analysis of azithromycin for Chlamydia trachomatis infection in women: a Canadian perspective.">Marra F, Marra C, Patrick DM. Cost-effectiveness analysis of azithromycin for Chlamydia trachomatis infection in women: a Canadian perspective. Can J Infect Dis 1997;8:202208. </ref><ref name="A controlled trial of a single dose of azithromycin for the treatment of chlamydial urethritis and cervicitis.">Martin DH, Mroczkowski TF, Dalu ZA, et al. A controlled trial of a single dose of azithromycin for the treatment of chlamydial urethritis and cervicitis. The Azithromycin for Chlamydial Infections Study Group. N Engl J Med 1992;327:921-925. </ref><ref name="A double blind study of single dose azithromycin and doxycycline in the treatment of chlamydial urethritis in males.">Nilsen A, Halsos A, Johansen A, et al. A double blind study of single dose azithromycin and doxycycline in the treatment of chlamydial urethritis in males. Genitourin Med 1992;68:325-327. </ref><ref name="Cost-effectiveness analysis of fi ve different antibiotic regimens for the treatment of uncomplicated Chlamydia trachomatis cervicitis.">Nuovo J, Melnikow J, Paliescheskey M, King J, Mowers R. Cost-effectiveness analysis of fi ve different antibiotic regimens for the treatment of uncomplicated Chlamydia trachomatis cervicitis. J Am Board Fam Pract 1995;8:7-16. </ref><ref name="Effi cacy of single-dose azithromycin versus doxycycline in the treatment of cervical infections caused by Chlamydia trachomatis.">Ossewaarde JM, Plantema FHF, Rieffe M, Nawrocki RP, De Vries A, van Loon AM. Effi cacy of single-dose azithromycin versus doxycycline in the treatment of cervical infections caused by Chlamydia trachomatis. Eur J Clin Microbiol Infect Dis 1992;11:693-697. </ref><ref name="Chlamydial cervicitis and urethritis: single dose treatment compared with doxycycline for seven days in community based practises.">Thorpe EM Jr, Stamm WE, Hook EW 3rd, et al. Chlamydial cervicitis and urethritis: single dose treatment compared with doxycycline for seven days in community based practises. Genitourin Med 1996;72:93-97. </ref><ref name="Azithromycin versus doxycycline for genital chlamydial infections: a meta-analysis of randomized clinical trials.">Lau CY, Qureshi AK. Azithromycin versus doxycycline for genital chlamydial infections: a meta-analysis of randomized clinical trials. Sex Transm Dis 2002;29:497-502. </ref>(근거수준 1)

 A   생식기 클라미디아 감염의 권장 항생제 요법
    ⋅Azithromycin 1g 경구 단회 요법 
 A  또는
    ⋅Doxycycline 100mg 1일 2회 경구 7일 요법
 B   환자의 낮은 복약 순응도가 예상되는 경우에는 azithromycin 1g 경구 단회 요법이 권장된다.