항생제 사용 용량
(Ref> 2012 Stanford guide to antimicrobial therapy 42nd ed.)
| Class, Agent, Name | Usual adult dosage | Preg risk |
|---|---|---|
| Natural penicillins
Benzathine penicillin G Penicillin G - |
-
600,000-1.2 million units IM q2-4wks Low: 600,000-1.2 million units IM per day High: ≥20 million units IV q 24hrs |
B
B |
| Penicillin V | 500 mg p.o bid, tid | B |
| Aminopenicillins
amoxicillin amoxicillin-ER amoxicillin-clavulanate Ampicillin - ampicillin-sulbactam |
-
250mg-1g po tid One 775mg tab po q D 500/125, 875/125 1tab po bid 250mg-500mg po q 6hr 50-200mg/kg IV/day 1.5-3g IV q 6hr |
B
B B B B |
| Extended spectrum
penicillins piperacillin - |
-
3-4g IV q 4-6hr (max 24g/day) for urinary tract infection: 2g IV q 6hr |
B |
| Antipseudomonal penicillins
piperacillin-tazobactam - - - |
-
standard dose (no pseudomonas) 3.375g IV q 6hr or 4.5g IV q 8hr standard dose (pseudomonas) 3.375g IV q 4hr or 4.5g IV q 6hr |
B |
| Carbapenems
Doripenem - Ertapenem Imipenem+cilastatin Meropenem |
-
intra abdominal, complicated UTI 500mg IV q 8hr (1hr infusion) 1g IV/IM q 24hr 0.5g IV q 6hr 0.5-1g IV q 8hr |
B
B C B |
| Cephalosporins
1세대 Cefazolin Cefadroxil Cephalexin 2세대 cefotetan cefoxitin cefuroxime cefaclor cefprozil |
-
- 1-1.5g IV/IM q 8hr (max 12g/day) 0.5-1g po q 12hr 0.25-1g po q 6hr (max 4g/day) - 1-3g IV/IM q 12hr 1g q 8hr-2g IV/IM q 6-8hr 0.75-1.5g IV/IM q 8hr 0.25-0.5 g po q 8hr 0.25-0.5 g po q 12hr |
B
B B B B B B B |
| cefuroxime axetil
3세대 cefoperazone-sulbactam cefotaxime ceftazidime ceftizoxime ceftriaxone cefdinir cefditoren pivoxil cefixime cefpodoxime proxetil ceftibuten |
0.125-0.5 g po q 12hr
- 1-2g IV q 12hr 1g q8-12hr to 2g IV q 4hr 1-2g IV/IM q 8-12hr 1-2g IV q 8-12hr 1-2g once daily 300mg po q 12hr or 600 mg q2 4hr 400mg po bid 400mg po bid 0.1-0.2g po q 12hr 0.4g po q 24hr |
B
B B B B B B B B B B |
| Macrolide
Azithromycin Clarithromycin |
-
0.5g IV per day (oral 제제는 질병에 따라 변동) 0.5g po q 12hr |
B
C |
| Tetracyclines
Doxycycline |
-
0.1 g po/IV q 12hr |
B |
| Fluoroquinolones
ciprofloxacin gemifloxacin levofloxacin moxifloxacin ofloxacin |
-
250mg po bid/400mg IV q 12hr 320mg po q 24hr 250, 500, 750mg po/IV q 24hr 400mg po/IV 24hr 200-400mg po bid |
C
C C C C |
| Amnioglycoside
Amikacin Gentamycin |
-
15mg/kg/day IV 3mg/kg q 8hr IV |
D
D |
| 기타
fosfomycin metronidazole - |
-
3g with water po times 1 dose Anaerobic infection: IV 7.5mg/kg q 6hr oral dose 1g qd |
B
B |
Preg risk: 임신시 사용가능여부 FDA category